Fact Checked

5-HTP Plus Review – Does this Product Really Work?

5-HTP Plus is a product that may improve your mood and reduce anxiety. It is a natural remedy that claims to encourage a calm, relaxed mood all day.


Advertising Disclosure

FTC Disclosure

We, Health Web Magazine, the owner of this e-commerce website, fully intends to comply with the rules of the Federal Trade Commission (FTC) regarding the use of endorsements, testimonials, and general advertising and marketing content. As a visitor to Health Web Magazine you should be aware that we may receive a fee for any products or services sold through this site.


This content may contain all or some of the following – product information, overviews, product specifications, and buying guides. All content is presented as a nominative product overview and registered trademarks, trademarks, and service-marks that appear on Health Web Magazine belong solely to their respective owners. If you see any content that you deem to be factually inaccurate, we ask that you contact us so we can remedy the situation. By doing so, we can continue to provide information that our readers can rely on for truth and accuracy.

Our Top Selections Box - Promotional Sales

Products shown in the section titled ‘Our Top Products’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. In order to comply fully with FTC guidelines, we would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links we will receive compensation. Health Web Magazine is an independently owned website and all opinions expressed on the site are our own or those of our contributors. Regardless of product sponsor relations, all editorial content found on our site is written and presented without bias or prejudice.

Overview Of 5-HTP Plus

Mood disorders are a growing concern in the 21st century. The biggest challenge to medics and patients alike is that mood disorders may not be pinned down to one particular cause. The effects of lack of moods might include lack of interest in normal activities, hopelessness, depression, and at the worst may lead to suicide.

5-HTP Plus has active ingredients that may help you fight mood changes and promote relaxation, leading to better health and healthy activities like better sleep patterns, appetite, and an overall healthy body. 5-HTP Plus may be the product to help promote a calm mood, maintain a positive outlook by balancing the body’s serotonin levels.

The product may help you control your mood for better physical, social and mental health. Through various 5-HTP Plus reviews, this review brings your attention to various features of the product that may help you use or ignore this product.

How Does 5-HTP Plus Work?

5-HTP (5-hydroxytryptophan) is a chemical product of the plant protein building block L-tryptophan that may help combat depression, anxiety, and sleep disorders such as insomnia and other ailments. 5-HTP is a naturally occurring amino acid that is involved in the synthesis of serotonin. By synthesizing this serotonin hormone, the product might stabilize mood, feelings of well-being, and happiness.

Who Is The Manufacturer Of 5-HTP Plus?

5-HTP Plus is manufactured by Natrol, a leader in minerals, vitamins, and supplements. Founded by Elliot Balbert in 1980, Natrol has evolved over the years to become amongst the known manufacturers in the industry. It claims to create quality and innovative products that help customers lead quality lives.

5-HTP Plus

5-HTP Plus Review – Health Web Magazine Images

What Are The Ingredients In 5-HTP Plus?

5-HTP Plus is made of several ingredients, but the following are listed on its bottle as active ingredients. They are:

5-hydroxytryptophan -5-HTP is an amino acid that the body produces and uses to synthesize the serotonin hormone. A deficiency in the hormone may lead to weight gain, depression, sleep disorders, and anxiety.

Several studies have revealed that continuous use of 5-HTP reduced the symptoms of depression, while one showed it as a possible cure for depression.

Vitamin B6 -Depression might be caused by the depletion of vitamin B6. Thus, taking a product with vitamin B6 may help reduce depression. Research claim that long-term use of vitamins, like B6, may fight depression and reduce the risk of relapse of depression.
Vitamin B12 -Vitamin B12 (Cyanocobalamin) like B6 may be important for a healthy and well-functioning nervous system. A robust nervous system might be able to ward off stress and depression easily. Vitamin 12 may be also vital in the body’s production of serotonin.

One study[1] claim that vitamin B12 deficiency may lead to twice the amount of depression. Therefore, the increase of Vitamin B levels might help in faster recoveries of depression and mood enhancement.

Calcium-Calcium has often been paired with vitamin D to regulate mood fluctuation in women attributed to PMS. Calcium plays a role in estrogen production and thus is vital in regulating PMS-related depression. Women who have higher calcium levels have been shown to have less stress compared to those who have lower levels.

The Science Behind 5-HTP Plus

5-HTP Plus might be a mix of natural body chemicals that help control mood and thus bring your body to the point of relaxation without introducing toxic chemicals. The supplement mainly contains calcium, 5-HTP, vitamins B12, and B6, which play a crucial role in the nervous system.

The presence of these natural body chemicals stimulates the body to produce serotonin, a hormone responsible for stabilizing mood, promoting relaxation and the feeling of happiness.

The supplement is all-natural and in an easy dissolving foam so that it may easily help patients get their moods right. The supplements might help you get your spirits high, have a good night’s sleep, and control your appetite. A good mood might generally impact your overall body health for a more fulfilled life.

What Are The Benefits Of 5-HTP Plus?

  • It may help to promote a calm and relaxed mood.
  • The product may help reduce the effects of depression, stress, and sleep disorders.
  • 5-HTP Plus may promote balanced serotonin levels for improved mood.
  • It might help to maintain a positive outlook on life.
  • The product may help reduce migraine frequency.
  • It may not be habit-forming, hence it might not make patients reliant on it.
  • The supplement is natural and may not have chemicals that are harmful to the body.

What Are The Drawbacks Of 5-HTP Plus?

  • Some patients have been taken ill with eosinophilia-myalgia syndrome (EMS) after consuming 5-HTP, so it is good to know the side effects.
  • The product’s manufacturer only offers a return in case the product is defective.
  • Do not use 5-HTP Plus with other supplements containing L-Tryptophan or 5-HTP.
  • 5-HTP Plus is prohibited for pregnant, lactating, or under the age of 18 years.

FAQs: Consumer Questions & Answers

In our research for this report, we found that consumers are frequently asking the following questions online in regard to 5-HTP Plus.

The active ingredients listed on the official website may be safe for your use. Patients should watch out for possible side-effects from 5-HTP.

Patients who need to take the product for depression, migraines, Parkinson's disease, or psychiatric disorders should consult with their physician before starting a dose. Do not use 5-HTP Plus with other supplements containing L-Tryptophan or 5-HTP. Do not use if you are pregnant, lactating, or under the age of 18 years.

The price offered by most independent retail websites is similar to the product's official website. It is a reasonably priced natural supplement.

Take one tablet and drain it down with water. It would be best if you only took a maximum of two pills a day. Any addition is an overdose and may lead to harmful side-effects.

The product's manufacturer only offers a return in case the product is defective. In case you buy from other retail websites, ask the retailer if there are offers for a free trial or refund policy.

5-HTP Plus reviews claim that the supplement had an impactful effect on the patients than depressants that patients were taking before taking on 5-HTP Plus. Thus, it might be a good product among other depressants.

Taking 5-HTP Plus before surgery leads to high serotonin levels that might lead to heart problems, shivering, and anxiety. A few patients have reported eosinophilia-myalgia syndrome (EMS) after taking the supplements.

5-HTP Plus may help restore good moods after a long day at work. It has generally helped many to have peaceful nights and has good 5-HTP Plus reviews.

What Are Consumers Saying About 5-HTP Plus?

Most 5-HTP Plus reviews are good as users report having more peaceful sleep and more productive hours at work.

Depression and anxiety are common disorders that can make daily tasks extremely challenging. Some estimates allege that approximately one in ten Americans suffer from some level of depression and/or anxiety. Symptoms of anxiety and depression include ongoing feelings of sadness accompanied by unease, irritability, tension, and nervousness. While some people require medication to deal with these occasionally crippling symptoms, others may find an all-natural product helpful. An all natural relaxation supplement should promote healthy neurological function. All ingredients should be clinically proven to reduce feelings of anxiousness, sadness, unease, irritability, tension, and nervousness.

Below you'll find some of the most effective natural nervousness relief supplements on the market today, in our opinion.


Try it now
#1 Serelax
Serelax Serelax
  • Quality of Ingredients*
  • Potential to Improve Sleep Pattern*
  • Relieve Feelings of Stress & Anxiety*
  • Supports Mental Focus & Clarity*
  • Induce Calmness & Tranquility*

Overall Rating


Read Full Review

St. John’s Wort
  • Quality of Ingredients*
  • Potential to Improve Sleep Pattern*
  • Relieve Feelings of Stress & Anxiety*
  • Supports Mental Focus & Clarity*
  • Induce Calmness & Tranquility*

Overall Rating


Read Full Review

Brillia Review
  • Quality of Ingredients*
  • Potential to Improve Sleep Pattern*
  • Relieve Feelings of Stress & Anxiety*
  • Supports Mental Focus & Clarity*
  • Induce Calmness & Tranquility*

Overall Rating


Read Full Review

Final Words

5-HTP Plus is a product that might help you relax for general health and boost your work productivity. The product may synergize several of its active ingredients to deliver quality to the customer consistently. It is promoted as a natural remedy that may work compared to synthetic remedies.

Most 5-HTP Plus reviews are good due to the relief the patient has gotten after using the product. However, 3 out of 4 testimonials express disappointment with the product, claiming some side effects like eosinophilia-myalgia syndrome (EMS) after taking the supplement. Furthermore, the manufacturer only offers a return in case the product is defective. We would suggest talking to your doctor about 5-HTP Plus, and perhaps look for a similar product in the same category.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information. *Results from using this product may vary. If you have a serious medical condition, a history of heart conditions, are pregnant or nursing, we recommend that you speak to your healthcare provider before using this, or any other health product and/ or supplement. The content provided on Health Web Magazine is only intended for your informational purposes and should not be regarded as a substitute for advice from a healthcare professional. It should not be used to diagnose, treat, cure, or prevent any health condition, and we will not be held responsible for any complications that may arise from you using it for any of those aforementioned reasons. All concerns regarding your personal health must be dealt with directly by your healthcare provider.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Products’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

0 Reviews for 5-HTP Plus

5-HTP Plus Review – Does this Product Really Work?
5-HTP Plus Reviewer Rating
3.5 / 5.0
5-HTP Plus Review – Does this Product Really Work?
Write a Review Please review the Guidelines before posting

Hints on how to write a helpful review

A great review should have the following qualities:

  • A helpful review should connect and engage with the readers using personal experience.
  • An excellent review provides the readers with cogent and unbiased information necessary to help them make the best choice.
  • A review must be well-formatted to make reading easier by using multiple paragraphs and avoiding caps.
  • The primary goal of your review must remain to provide accurate and non-salesy information.
  • Above all, let your review be fair and honest.

We have high level of professional editorial section with zero tolerance policy on fake reviews.

To maintain the genuineness of our brand, we ensure all customer reviews submitted to us are verified and confirmed before publishing. Though we might not be a 100% accurate, however, we try our best to ensure being next to best. For a thorough verification of submitted reviews, we spend close to 7 working days before allowing any customer review to be published since we also work on the earliest submissions first.

Leave a Reply

Your email address will not be published. Required fields are marked *

100 characters remaining.

Your Rating:05

Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Health Web Magazine Terms of Use and such conduct will not be tolerated.

5000 characters remaining.

Thanks for submitting your comment!


Get the latest in healthy living, nutrition & fitness, mental wellbeing, beauty & skincare, and more, straight to your inbox!


Your Privacy is important to us

Medical Disclaimer: The content published on our website, Health Web Magazine, is to inform and educate the reader only and not a substitute for professional medical advice from your doctor or other health care provider. If you have a specific health question or concern you must consult with a qualified medical professional and in the case of an emergency, immediately contact your local emergency services. Health Web Magazine and the publisher of this content take NO responsibility for any detrimental health issues or injuries that result from following advice found in articles, reports/overviews, or other content on our website. All visitors to Health Web Magazine, particularly pregnant and nursing women and individuals taking over-the-counter or prescribed medication, must consult with their physician before starting a new supplement or making any changes to their diet or exercise plan.

All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. © 2021. All Rights Reserved. All opinions expressed on this website are the opinion of and were written by Admark LLC, owners/operators of this website. Disclaimer: The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Your use of this website indicates your agreement to these websites published terms of use and all site policies.


All Health Web Magazine content is thoroughly reviewed and/or fact-checked by a team of health industry experts to ensure accuracy.

In keeping with our strict quality guidelines, we only cite academic research institutions, established health journals, or peer-reviewed studies in our content. You will be able to find links to these sources by clicking the numbers in parentheses (1, 2, etc.) that appear throughout our content.

At no time do we advise any of our readers to use any of our content as a substitute for a one-on-one consultation with a doctor or healthcare professional.

We invite you to contact us regarding any inaccuracies, information that is out of date or any otherwise questionable content that you find on our sites via our feedback form.