Estro-500 Review – Does This Product Really Work?

Estro-500 is a topical cream that is designed to provide relief to women suffering from the symptoms of menopause.


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Overview Of Estro-500

The transition of menopause is experienced by 1.5 million women every year and often involves insomnia, fatigue, hot flashes, night sweats, and joint pain.

There are several treatment options for the management of menopause symptoms. However, menopause relief products are popular because of the severe side effects associated with hormone replacement therapy.

Thus, Estro-500 is a topical cream that is formulated to alleviate symptoms of menopause, such as hot flashes, anxiety, and mood swings. Continue reading to see what Estro-500 reviews have indicated about this product. 

How Does Estro-500 Work?

Estro-500 contains 80% estriol and 20% estradiol, which are bio-identical to human estrogen. According to the brand, these ingredients help in delivering their claims. These ingredients mimic the mechanisms of estrogen in the company, which can fool the body into thinking that there is enough estrogen circulating. However, the company has not given detailed information. Thus, it is unclear how exactly Estro-500 works.

Who Is The Manufacturer Of Estro-500?

Estro-500 is manufactured by Natural Living Company, a company based in Las Vegas, NV. They have been in business since 2006 and are known for manufacturing several different vitamins, dietary supplements, and cosmetic creams.

All products manufactured by the Natural Living Company are made in the U.S. according to GMP specifications.


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What Are The Ingredients In Estro-500?

Here are the primary ingredients found in Estro-500:

Estriol – Also known as Oestriol or E3, is an estrogen hormone. 

According to one study[1], oral estriol therapy significantly reduced hot flashes, night sweats, and insomnia. Estriol is therefore considered to be a safe alternative for the relief of menopausal symptoms.

Grapefruit Seed Extract – This product has been used previously as a natural remedy for several health problems.

Research in the Menopause Journal indicates that grapefruit seed extract efficiently improves the physical and psychological symptoms of menopause in middle-aged women.

The Science Behind Estro-500

Estro-500 contains estriol, estradiol, and grapefruit seed extract that may help provide relief to women suffering from symptoms of menopause, including hot flashes, anxiety, mood swings, and weight gain.

However, there is only some clinical research regarding Estro-500 and its ingredients. Despite this, menopause relief products are more common because hormone replacement therapy has serious side effects, which might be avoided with these products.

What Are The Benefits Of Estro-500?

  • This topical cream may provide relief for women suffering from menopause.
  • The product doesn’t contain any parabens and fragrances.
  • It has no artificial colors and is sulfate-free.
  • The product comes in an airless pump dispenser, making it mess-free.

What Are The Drawbacks Of Estro-500?

  • There are no studies regarding the safety or efficacy of Estro-500.
  • The product may lead to skin allergies or reactions.
  • The company does not state the exact quantity or composition of each ingredient.

FAQs: Consumer Questions & Answers

In our research for this report, we found that customers often ask the following questions online with regards to Estro-500.

Estro-500 is considered safe to use unless you are pregnant or nursing. It is recommended to always consult with a healthcare professional before using any new products.

Estro-500 is sold in selected retail stores and might be purchased online from anywhere in the business as you may purchase it without a prescription. The price of this product is reasonable in comparison to other menopause relief supplements.

Apply two pumps of this cream to clean and dry skin before sleeping. It may be applied up to twice a day. Furthermore, you may apply it to the inner thigh area as well.

The official website states that they do not offer a free trial for the product. However, they do offer a money-back guarantee on unopened bottles of Estro-500.

Estro-500 may provide relief to women suffering from symptoms of menopause by alleviating their hot flashes, night sweats, anxiety, and insomnia.

There have been no severe side effects reported. However, Estro-500 may cause mild irritation to the skin.

A hypersensitive reaction may occur if the consumer is allergic to any ingredients. Therefore, it is recommended to read the ingredient list thoroughly before using any new products on your skin.

Many of the Estro-500 reviews suggest that they were happy with the product as it helped alleviate the symptoms of menopause using a simple topical cream.

What Are Consumers Saying About Estro-500?

The definite Estro-500 reviews indicate that there was a reduction in their hot flashes and insomnia problems. However, several negative reviews about this product state that the cream did not offer significant relief to menopause symptoms. In contrast, other studies demonstrate that there was a minimal effect of this cream.

Fortunately, natural therapies for menopausal symptoms such as weight gain, hot flashes, night sweats, decreased libido, and mood swings are available. Since many women experience weight gain during menopause, many natural menopause supplements contain herbs and botanicals that support a healthy metabolism. Menopause supplements should be evaluated on proven ingredients, ability to reduce hot flashes and night sweats, ability to provide hormonal balance and boost libido and its overall value.

Below you’ll find some of the most effective menopause supplements on the market today, in our opinion.

Our Top Choices of 2022


MenoquilSignificant reduction in menopausal symptoms within the first 3 weeks!

Menoquil Reviews
4.5/5 (8327 Ratings)
Eliminates Hot Flashes 98%
Increases Levels Of Estrogen 99%
Combats Menopausal Weight Gain 98%
Promotes Restful Sleep 98%
Diminishes Vaginal Dryness 97%


  • Quickly reduces the severity of hot flashes and night sweats
  • Alleviated multiple symptoms for 98% of users
  • Restores complete hormonal balance
  • Works on emotional symptoms such as anxiety and mood swings
  • Reduces the risk of menopausal weight gain
  • Boosts the libido and eases vaginal dryness
  • Prevents bone loss and the risk of osteoporosis
  • Combats fatigue and increases energy levels
  • Can be used at any stage of menopause
  • 100% safe for long-term use
  • There are no reports of unpleasant or harmful side effects
  • Key active ingredients are clinically proven
  • Natural formula with no artificial substances
  • Company offers a 60-day money-back guarantee
  • Orders over $60 are eligible for free shipping
  • Product is shipped in plain packaging for privacy
  • Customer service department is friendly and knowledgeable
  • Customers can try the Quick Starter Travel Pack
  • There is no mandatory auto-shipping or subscription plan


  • Menoquil is not sold in retail stores
  • High consumer demand results in low stock at times

The Bottom Line

When we set out to produce a list of the top menopause supplements currently available, we looked at numerous brands, but of all the products we tested, Menoquil was the clear winner, producing outstanding results in less than 2 weeks of use. What really impressed us about this doctor-developed brand was the fact that it works on multiple symptoms of menopause, not just one or two, and can be used at any stage, from perimenopause right through to post-menopause.

While the clinical testing data for Menoquil speaks for itself, proving that it safely restores complete hormonal balance for Promotes Restful Sleep & Boosts Energy*, the real-life results it produced for the thousands of women who have taken it are remarkable, which is why it has such an incredibly high satisfaction rating among users. Indeed, in our own trials, 100% of the testers reported feeling a significant reduction in the frequency and severity of hot flashes, fast relief from night sweats, and a more stable mood with less stress and anxiety. Additionally, a remarkable number of women also stated that their energy levels had increased , and they’d also lost weight, particularly around their abdomen: this not only improved their confidence but combined with the boost in libido and reduction in vaginal dryness, allowed them to enjoy greater intimacy and sexual pleasure.

It should come as no surprise that Menoquil works as well as it does when you look at the key active ingredients that the leading researchers at Pharmaxa Labs have included in this powerful formula. The all-natural blend combines proven botanicals such as Black Cohosh, Soy Isoflavones, and Chaste Berry, all included in their optimal concentrations and specifically designed to work synergistically for maximum results. And, unlike some menopause relief supplements, Menoquil contains absolutely no hormones or synthetic substances so there’s no danger of side effects, even with extended use.


We have absolutely no doubt that Menoquil will work just as well as the manufacturer claims, but we do acknowledge that supplements work differently depending on the individual. That’s why we were pleased to see that Menoquil is fully backed by a 60-day satisfaction guarantee, meaning that every woman can try it for herself completely risk free. Additionally, Pharmaxa Labs offers discounts and free shipping on all multi-bottle purchases, and they respect the privacy of their customers by sending each order in plain packaging.

We know that menopause can be a challenge at any stage, but it can also be an exciting time in a woman’s life. By reducing all common symptoms safely and for the long-term, Menoquil allows women to get through this transitional time feeling healthy, happy, and in full control of their menopause!


Menoquil customer reviews over the internet

Menoquil Reviews
4.5/5 (8327 Ratings)
“I Am Using Menoquil Since Last 8 Years. I Feel 150% Better With Menoquil And I Would Not Go A Day Without It. I Really Love It!”

Kim K, Age 54

“I Highly Recommend Menoquil, It's One Of The Best For Me And Anybody!”

Jill R, Age 53


#2. Membrasin

(4.2/5) 4625 Reviews
Eliminates Hot Flashes 89%
Increases Levels Of Estrogen 90%
Combats Menopausal Weight Gain 87%
Promotes Restful Sleep 88%
Diminishes Vaginal Dryness 87%


  • Is specifically designed to help with vaginal dryness
  • There is a 6-month money-back guarantee


  • It doesn’t work on all menopause symptoms
  • It has received mixed reviews regarding its effectiveness
  • Free samples aren’t offered
  • Some users have reported mild side effects

The Bottom Line

Membrasin seems to be a high-quality supplement that is made specifically for women who experience vaginal dryness, a common symptom of menopause. It consists of several omega fatty acids and vitamins that are likely suitable for most women, although some have experienced some mild side effects. In addition to alleviating vaginal dryness, Membrasin may also work to reduce the severity of night sweats, although it should not necessarily be relied upon to do so, and most menopausal women may need to use an additional product to help with all their physical and emotional symptoms.


#3. Equelle

(3.9/5) 4235 Reviews
Eliminates Hot Flashes 88%
Increases Levels Of Estrogen 84%
Combats Menopausal Weight Gain 85%
Promotes Restful Sleep 83%
Diminishes Vaginal Dryness 82%


  • The key ingredient is clinically proven
  • It is designed to work on multiple menopause symptoms


  • It only contains one key active ingredient
  • Customers have to subscribe if they want a discounted price
  • Some users report that the pills are hard to swallow
  • The key ingredient is a common allergen

The Bottom Line

Even though the key active ingredient in Equelle , S-equol, is said to have been proven effective in clinical testing, it is a concern that this supplement relies solely upon one active ingredient to produce results. Moreover, S-equol consists of fermented soy germ, a common allergen that may not be suitable for some women. It should also be noted that to purchase Equelle at the discounted price, the consumer is required to sign up for the company’s subscription plan, which is not something all individuals are comfortable with.


- Estro-500 Customer Reviews
  • Barbara: Helped Reduce Hot Flashes. They work wonders!!! Highly recommend.
    Star Ratings
  • Jessica: Excellent relief from hot flashes! Works for regulating hot flashes.
    Star Ratings
  • Flora: Best product for menopause relief. Hot Flashes Virtually Gone
    Star Ratings
  • Gretta: Works for regulating hot flashes. Helps so much with hot flashes and mood.
    Star Ratings
  • Roxanne: This works with my menopause issues. Great supplement that definitely helps with hormone balance.
    Star Ratings
  • Juliet: Very satisfied with this purchase. Hot Flashes Fading Fast.
    Star Ratings

Final Words

Estro-500 is a topical cream that is designed to improve the symptoms of menopause, such as hot flashes, night sweats, anxiety, and insomnia.

There are several positive as well as negative Estro-500 reviews, suggesting the lack of encouraging findings regarding the efficacy of this cream. Therefore, it is unclear whether this cream may work in the same manner for all consumers and provide everyone with the same benefits and drawbacks.

In addition to this, it is advised not to use any cream on your skin without consulting with a healthcare professional to ensure it is suitable for you and will not result in adverse skin reactions.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information. *Results from using this product may vary. If you have a serious medical condition, a history of heart conditions, are pregnant or nursing, we recommend that you speak to your healthcare provider before using this, or any other health product and/ or supplement. The content provided on Health Web Magazine is only intended for your informational purposes and should not be regarded as a substitute for advice from a healthcare professional. It should not be used to diagnose, treat, cure, or prevent any health condition, and we will not be held responsible for any complications that may arise from you using it for any of those aforementioned reasons. All concerns regarding your personal health must be dealt with directly by your healthcare provider.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Products’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

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Estro-500 Review – Does This Product Really Work?
Estro-500 User Review Rating
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Estro-500 Review – Does This Product Really Work?
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