Corium 21 Reviews – Does This Product Really Work?

4.3/ 5.0

Corium 21 is an anti-aging formula that may be designed to improve the appearance of common skin conditions, diminish aging signs, and improve overall skin health.


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Overview Of Corium 21

According to the brand, the product may be formulated with a combination of ingredients that may help to improve the appearance of common aging signs such as wrinkles, fine lines, crow’s feet, hyperpigmentation, and skin dullness. 

It may also be useful against common skin conditions like rosacea, sunburn, eczema, and acne. The product may be sold online for around the price of many similar formulas and has received mixed reviews. 

In this review, we will discuss all you may need to know about the product, including details like how it may be supposed to work, the manufacturer, ingredients, and possible adverse reactions.

Corium 21 Reviews alongside other information may help guide your decision. You may leave other questions you may have about the product in the comment section below. 

How Does Corium 21 Work?

Corium 21 may be said to be formulated with a combination of ingredients like Aloe Vera and Japanese Green tea found to contain polyphenols, soothe the skin, and help reduce wrinkles and other aging signs.

It may also contain Panax ginseng shown in numerous studies to improve the appearance of aging skin. The nutrients, vitamins, and emollients may also help improve the appearance of aging skin.

The product may claim to minimize the appearance of wrinkles, fine lines, hyperpigmentation, dryness, and other aging signs while also being useful against common skin conditions like eczema, sunburn, varicose veins, itchiness, rosacea, and acne scars.

Who Is The Manufacturer Of Corium 21?

Corium 21 is manufactured by Corium 21 Inc., a company established in 1994. According to the brand, it may be formed after they extensively tested the available aloe-based products. They were unsatisfied with the results.

The brand eventually formulated their aloe product using what they referred to as “the most useful aloe available.” Corium 21 may be released in 1996. Over the years enjoyed patronage from many new customers around the world.

Today, it may be available on the brand’s official website and through licensed independent distributors for around the price range of many similar products.

Corium 21

Corium 21 Review – Health Web Magazine Images

What Are The Ingredients In Corium 21?

Outlined and discussed below are the key ingredients in this formula.

Aloe Barbadensis Leaf Juice – Claimed to be one of the most potent varieties of Aloe Vera[1], the ingredient may be used in skincare and wellness formulations for its anti-inflammatory, analgesic, and pain-soothing qualities.

It may be used for its ability to significantly calm inflamed skin, reduce pain, and itching from common skin conditions. It may also reduce the appearance of wrinkles and other aging signs.

Panax Ginseng – Panax Ginseng is a staple in many formulas for wellness. In studies, topical panax ginseng root may be found to increase skin hydration, improve texture, and fade uneven skin tone.

Some studies also suggest that the herb may improve the appearance of wrinkles and increase the skin’s firmness.

Japanese Green Tea leaf extract – Japanese Green tea leaf extract is rich in polyphenols and different catechins. In studies, these compounds may be found to prevent premature aging, soothe irritation and redness, reduce acne, and improve skin moisture levels. 

Other ingredients in the formula may include glyceryl stearate (emollient and emulsifier), isopropyl palmitate (thickening agent, emollient, and moisturizer), phenoxyethanol (preservative), and cetyl alcohol (emollient and emulsifier).

The Science Behind Corium 21

Corium 21 is said to be formulated with a selection of ingredients that may help improve various skin conditions and diminish the appearance of common aging signs.

The cream may contain aloe barbadensis leaf juice, green tea leaf extract, Panax ginseng, and others like emollients that may help reduce aging signs like wrinkles, fine lines, dryness, dryness and dullness by boosting skin moisture and providing antioxidant protection.

It may also improve the appearance of skin conditions like rosacea, sunburn, eczema, and acne scars.

While the key ingredient aloe has been studied widely and may be found to hold many beneficial qualities for aging skin, we think the product may be more useful against aging if it contained other known anti-aging ingredients like hyaluronic acid, peptides, and collagen.

What Are The Benefits Of Corium 21?

  • It contains aloe Barbadensis leaf juice, which may deeply hydrate skin layers.
  • It may improve common skin conditions like psoriasis, eczema, and sunburn.
  • The product may improve skin moisture levels and improve suppleness.
  • It may improve the appearance of common aging signs.

What Are The Drawbacks Of Corium 21?

  • The quantities of the main ingredients are unknown.
  • It may not contain some helpful anti-aging ingredients.
  • No independent scientific studies on the product may be available.
  • Some users experienced side effects such as itching and burning sensation and reported that the cream did not work for them at all.

FAQs: Consumer Questions & Answers

In our research for this report, we found that consumers are frequently asking the following questions online regarding Corium 21.

While the product may contain some known natural ingredients and no severe adverse reactions linked with its use, it may still contain additives that may cause certain side effects.

And like most products, it may not be suitable for use by all, especially people with sensitivity to any of the ingredients.

It may also not be used on broken skin and by people younger than 18 unless otherwise advised by a health professional.

The product is within the price range of many anti-aging formulas though pricing may differ slightly from user to user.

Apply the cream on your face and body after your cleansing routine as a moisturizer. It may be applied at least thrice daily or more. If used on a rash, inflammation, or an itch until it reduces.

The manufacturer mentions return policy with money-back guarantee. Besides, they also offer free 1 year, 100% replacement.

Corium 21 is within the price range of many aloe products for aging and inflammation and may contain some of the same ingredients, and as these products, it may not work as claimed for all users.

Some of the side effects that may be experienced include itching, redness, and peeling.

You decide. It may contain some known ingredients, though as it is a formulation also designed to reduce the appearance of some aging signs, we think it may be more useful with other known anti-aging ingredients.

What Are Consumers Saying About Corium 21?

Corium 21 Reviews are mixed. While some users said they may experience improvements in their skin’s inflammation and in aging signs like dryness and skin dullness from use, some said it may not help them.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Rating Table Rating Table

Our Top Products

Try it now
Stemuderm Rating
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Produces visible results in less than 2 weeks
  • 100% of users experienced a reduction in wrinkle depth
  • Firms skin and restores elasticity
  • Provides long-lasting hydration to eliminate dryness
  • Supports an increase in collagen and elastin production
  • Reduces repetitive muscle movements to stop wrinkle development
  • Strengthens the protective skin barrier
  • Drastically improves long-term skin health
  • Prevents damage from toxins, pollutants, and environmental factors
  • Can be used on all skin types, including sensitive
  • All key ingredients are backed by solid clinical data
  • Manufacturer offers a full money-back guarantee and free shipping
  • Customers can try the product by ordering the Quick Starter Travel Pack
  • Customers do not have to sign up for an auto-shipment or subscription plan


  • Stemuderm cannot be purchased in retail stores
  • High consumer demand results in low stock occasionally

The Bottom Line

We looked at numerous brands of wrinkle creams during our process of compiling a list of the top brands on the market, but one treatment stood out from all the others, and that’s Solvaderm’s Stemuderm.

It’s no surprise that Stemuderm is one of Solvaderm’s best selling products when you consider that it visibly improves the appearance of the skin in less than 2 weeks of use! Rich in clinically proven key active ingredients, this dermatologist developed cream works on multiple signs of aging, including deep-set wrinkles across the forehead and around the mouth, fine lines and crow’s feet around the eyes, and even areas of hyperpigmentation such as age spots. Not only that, but within only a few applications, Stemuderm eliminated dry, flaky patches, locking in moisture, and making the skin smooth, hydrated, and soft to the touch.

Stemuderm Before After

Because Stemuderm produces powerful results in such a short period of time, it’s quickly become a consumer favorite with a satisfaction rating of more than 97%. Almost all Stemuderm users say that it’s an essential part of their morning and evening skincare routine and they would never stop using it. Indeed, the individuals who tested the cream as part of our own extensive review process said that they were particularly impressed at how easily Stemuderm could be incorporated into their current regimen, regardless of their skin type. They also noted that, with regular use, Stemuderm not only maintained the dramatic anti-aging effects they’d already achieved within the first initial few weeks of use but continued to improve the overall health and appearance of their skin, making it look refreshed and rejuvenated. Additionally, their complexion became evenly toned, with a complete absence of redness, and a more uniform texture.

When you look at the incredible results of clinical studies performed on the key active ingredients contained in Stemuderm, it’s easy to see why this treatment works as well as it does, with 100% of users seeing a drastic improvement after only a few weeks of use. For example, in one study looking at the anti-aging benefits of Matrixyl 3000, a substance that supports the production of collagen and elastin, participants experienced a 45% reduction in the area occupied by wrinkles. and in another scientific trial, women using a cream containing the peptide Acetyl Hexapeptide-8, demonstrated a decrease in wrinkle depth by as much as 60% within just 30 days.

While it is appreciated that the manufacturer of Stemuderm, Solvaderm, offers a money back guarantee on all their products including this one, we doubt that anyone would have a reason to return it. More than just a wrinkle cream, this truly is a multi-action skin treatment that can be used by individuals of all ages, whether they want to reverse existing damage and restore a youthful complexion, or prevent lines, wrinkles, and discoloration from developing in the first place.

Miami MD
#2 Miami MD
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Has many positive customer reviews
  • It was formulated by doctors


  • It is only available from the official website
  • The customer service department may be hard to contact
  • It may irritate sensitive skin
  • Ingredient amounts aren’t disclosed

The Bottom Line

Overall, the anti-aging treatment Miami MD appears to be a well-made and not overly expensive cream that provides multiple benefits for the skin. However, there are some negative aspects regarding the product too, with reports of it causing irritation for individuals with sensitive skin, and even a few consumers saying it made their complexion dry, which is the opposite of what a cream of this type should do. It would also be helpful if the manufacturer offered free samples of their cream and while there is a refund policy, some individuals have said that contacting the company’s customer service department is difficult.

#3 Drmtlgy
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Products in the range are suitable for all skin types
  • There is a 60-day money back guarantee


  • Drmtlgy products aren’t available in retail stores
  • Clinical study data for product formulas is not available
  • Drmtlgy is more expensive than comparable brands
  • Independent customer reviews are limited

The Bottom Line

The Drmtlgy brand offers several different skincare treatments, including a cleanser, SPF cream, and Needle-less serum, which according to the manufacturer is their best-selling product. The website for the brand is well-produced and reasonably informative and the formulas certainly contain some popular anti-aging key ingredients. However, the products are more expensive than similar brands and there is no solid evidence of successful clinical results provided on the website for prospective customers to review before making a purchase.

Your skincare routine is only as good as the products you use. Good, high-quality products are safe and effective and may come in particular formulations for sensitive skin and other issues. They can improve the texture and appearance of your skin while protecting it from the effects of the sun, pollutants, and other problems that can also have a negative impact on your health. Below you will find our subjective assessment of the Corium 21 based on the strength of the available information and our estimation of its efficacy for the Corium 21.

Corium 21
Corium 21
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture

Overall Rating

Try It

Stemuderm - A Better Alternative?

Diminishes Wrinkles & Fine Lines
Promotes Skin Cell Regeneration
Boosts Hydration
Promotes Good Skin Health
Improves Skin Tone & Texture

In as little as 28 days of regular use, Stemuderm dramatically reduces signs of aging on all areas of the face, including the forehead, cheeks, and around the mouth and eyes.

Stemuderm transforms the skin within weeks, making it visibly firmer, evenly toned, and overall more youthful. Stemuderm also provides long-lasting protection for the skin with its inclusion of innovative plant-based growth enzymes which, as numerous studies have shown, radically slow the aging process and increase skin cell longevity. When used twice a day as recommended by the manufacturer, Stemuderm has been proven to produce significant results, with many users seeing benefits within the first few applications.

You can find out more about Stemuderm now.

Read More About Stemuderm Nowarrow

Final Words

Corium 21 is a skincare product that may be designed to improve the appearance of common skin conditions like eczema, rosacea, psoriasis, and aging signs like wrinkles, fine lines, and skin dullness and dryness.

It is said to be formulated with a useful form of aloe and other ingredients that may be useful against the specified health conditions.

Corium 21 Reviews on their part have been mixed. And like us, some reviewers said they may feel the cream would have been more helpful with other useful ingredients.

Take into consideration the pros and cons such as the use of some ingredients, it's possible effects on skin conditions and aging signs, the unavailability of independent clinical trials and the possible side effects before you may buy.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Choice’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.


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