DermaFreeze365 Reviews – Does This Product Really Work?

DermaFreeze365 is an anti-aging formula designed to bring about an immediate reduction in the appearance of common facial aging signs. 


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Overview Of DermaFreeze365

The product is designed to be a quick anti-aging treatment for common facial aging signs such as wrinkles and fine lines. According to the brand, it is intended to be a “safer” replacement for more invasive anti-aging solutions, such as fillers, Botox, and surgery. 

It is said to work by freezing facial muscles to diminish fine lines and wrinkles promising buyers results in just 10 minutes. The ingredient is aminobutyric acid, a natural muscle relaxant supposedly efficient at reducing the tension of facial muscles and bringing about a smoother, fuller, and younger face even though not entirely free of adverse effects. 

In this review, we will share all potential buyers who should know about the product. It will include details such as the ingredients, manufacturer, the science behind the product, and the possible adverse reactions. 

Dermafreeze365 Reviews online will also be discussed here for current and past user opinions on the product. You may leave other questions you have about the product in the comment section below. 

How Does DermaFreeze365 Work?

DermaFreeze365 is an anti-aging product intended to be a reliable alternative to invasive anti-aging solutions such as surgery, fillers, and botox. The product, also said to be clinically-tested, promises about 50 – 90% reduction of visible lines and wrinkles resulting from a younger-looking, smoother, and fuller complexion.

Other key ingredients contained in the formula include sesame seeds oil, panax ginseng, eugenol, butylene glycol, licorice root extract, and jiaogulan extracts said to be added for their antioxidant, skin-brightening and protective effects amongst other benefits. 

Who Is The Manufacturer Of DermaFreeze365?

DermaFreeze365 is manufactured by JocottBrands, a skin care company established in 1996. The brand based in the United States formulates and markets a wide range of skincare products claiming to be clinically tested, just like DermaFreeze365.

The products are also claimed to be made with top grade ingredients following cosmetics production guidelines. 

On review and retail sites where products by JocottBrands are listed, we found no complaints of severe adverse reactions even though the reviews have been mixed.

Overall, JocottBrands appears to be a relatively good company with some competitively priced mid-range products for all skin types. 


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What Are The Ingredients In DermaFreeze365?

Outlined here are the primary ingredients in DermaFreeze365:

Aminobutyric Acid – The key ingredient in this anti-aging formula, aminobutyric acid [1] is a naturally occurring amino acid. It is commonly used in anti-aging formulas for its ability to “freeze” muscles and reduce the appearance of lines and wrinkles.
Sesame Seed Oil – A key ingredient in skincare and some wellness formulations, the sesame seed oil is often added for its moisturizing fatty acids essential for improving skin appearance and health. It is also said to contain significant amounts of vitamin E, E, and B, known to hold skin-repairing and regenerative qualities.
Licorice Root Extract – Licorice root extract is another ingredient commonly used in skin care formulations for its antioxidant and anti-inflammatory qualities. Research suggests that it may also brighten and provide the skin with moisture, though, may also be irritating to certain skin types due to its aromatic nature.

Other ingredients in the formula include Jiaogulan extract for its healing and rejuvenating effects, panax ginseng to help boost collagen production, eugenol for its antibacterial qualities and solvent effects, and butylene glycol added for its conditioning/thinning/solvent effects.

The Science Behind DermaFreeze365

DermaFreeze365 is an anti-aging formulation that may help diminish the appearance of common aging signs. The product is said to contain ingredients such as aminobutyric acid, a known muscle relaxant added for its ability to relax/freeze fine lines and wrinkles, sesame and licorice for their antioxidant and anti-aging effects, panax ginseng for its collagen-boosting effects, alongside others like jiaogulan extract for its antioxidant and skin-renewing effects amongst other benefits.

Together, they supposedly boost the health and appearance of aging facial skin. While DermaFreez365 contains some helpful natural ingredients, it also contains some potentially harmful ones like butylene glycol, eugenol, and others known to be pore-clogging, skin-suffocating, and acne-worsening. 

What Are The Benefits Of DermaFreeze365?

  • The product may work quickly to reduce aging signs.
  • It may help improve skin complexion and texture.
  • Applying it may make the skin smoother and plumper.
  • DermaFreez365 helps remove skin irregularities.

What Are The Drawbacks Of DermaFreeze365?

  • There are no third-party clinical studies on the product.
  • DermaFreez365 contains potentially harmful ingredients.
  • The outcome may vary among users.
  • There are no free trials offered by the company.
  • The return window is somewhat limited.

FAQs: Consumer Questions & Answers

In our research for this report, we found that consumers are frequently asking the following questions online in regard to DermaFreeze365.

While the gel contains some known all-natural ingredients, it also contains potentially harmful ones. Hence, it should only be used as advised by a health professional and avoided if sensitive to any of them.

Also, the product may not be used by people 18 and younger, people on similar anti-aging products, or broken skin. It should be discontinued, and medical attention sought if severe adverse reactions are experienced with use.

DermaFreeze365 is sold on the official website and compared to many similar products. It is moderately priced though this may differ slightly among retailers.

Apply the product on a thoroughly cleaned and dried face, massaging gently into the problem areas such as the mouth, eyes, and forehead. Then, wait about 10 minutes before applying other products like moisturizers.

The brand does not provide free trials on the product. While they provide refunds, they do not accept returns on over half-used or empty products. The qualifying products must also be returned within a few days of the purchase delivery date.

DermaFreeze365 contains the same key ingredient contained in some instant fine lines and wrinkles removal anti-aging formulas. However, it is more affordable than many of these products, it may cause certain side effects, and the results might vary.

Some of the side effects that may be experienced from using the product include irritation, acne, peeling, and inflammation/redness.

DermaFreeze365 has a low price and may work against fine lines, wrinkles, and other aging signs. It, however, contains certain irritants, toxins, and allergens that may be damaging over time.

What Are Consumers Saying About DermaFreeze365?

DermaFreeze365 Reviews online are few but mixed with many negatives. While some reviewers said they noticed and liked the improvements in their fine lines and wrinkles appear, some said it felt too unnatural to leave on.

Some also complained about the product becoming greasy the entire day and some about side effects, such as breakouts and redness.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Choices of 2021


StemudermBest-Selling Anti-Wrinkle Dermatological Formula!

Stemuderm Reviews
4.5/5 (8327 Ratings)
Diminishes Wrinkles & Fine Lines 98%
Promotes Skin Cell Regeneration 99%
Boosts Hydration 98%
Promotes Good Skin Health 98%
Improves Skin Tone & Texture 97%


  • Produces visible results in less than 2 weeks
  • 100% of users experienced a reduction in wrinkle depth
  • Firms skin and restores elasticity
  • Provides long-lasting hydration to eliminate dryness
  • Supports an increase in collagen and elastin production
  • Reduces repetitive muscle movements to stop wrinkle development
  • Strengthens the protective skin barrier
  • Drastically improves long-term skin health
  • Prevents damage from toxins, pollutants, and environmental factors
  • Can be used on all skin types, including sensitive
  • All key ingredients are backed by solid clinical data
  • Manufacturer offers a full money-back guarantee and free shipping
  • Customers can try the product by ordering the Quick Starter Travel Pack
  • Customers do not have to sign up for an auto-shipment or subscription plan


  • Stemuderm cannot be purchased in retail stores
  • High consumer demand results in low stock occasionally

The Bottom Line

We looked at numerous brands of wrinkle creams during our process of compiling a list of the top brands on the market, but one treatment stood out from all the others, and that’s Solvaderm’s Stemuderm.

It’s no surprise that Stemuderm is one of Solvaderm’s best selling products when you consider that it visibly improves the appearance of the skin in less than 2 weeks of use! Rich in clinically proven key active ingredients, this dermatologist developed cream works on multiple signs of aging, including deep-set wrinkles across the forehead and around the mouth, fine lines and crow’s feet around the eyes, and even areas of hyperpigmentation such as age spots. Not only that, but within only a few applications, Stemuderm eliminated dry, flaky patches, locking in moisture, and making the skin smooth, hydrated, and soft to the touch.

Because Stemuderm produces powerful results in such a short period of time, it’s quickly become a consumer favorite with a satisfaction rating of more than 97%. Almost all Stemuderm users say that it’s an essential part of their morning and evening skincare routine and they would never stop using it. Indeed, the individuals who tested the cream as part of our own extensive review process said that they were particularly impressed at how easily Stemuderm could be incorporated into their current regimen, regardless of their skin type. They also noted that, with regular use, Stemuderm not only maintained the dramatic anti-aging effects they’d already achieved within the first initial few weeks of use but continued to improve the overall health and appearance of their skin, making it look refreshed and rejuvenated. Additionally, their complexion became evenly toned, with a complete absence of redness, and a more uniform texture.

Stemuderm Before After

When you look at the incredible results of clinical studies performed on the key active ingredients contained in Stemuderm, it’s easy to see why this treatment works as well as it does, with 100% of users seeing a drastic improvement after only a few weeks of use. For example, in one study looking at the anti-aging benefits of Matrixyl 3000, a substance that supports the production of collagen and elastin, participants experienced a 45% reduction in the area occupied by wrinkles. and in another scientific trial, women using a cream containing the peptide Acetyl Hexapeptide-8, demonstrated a decrease in wrinkle depth by as much as 60% within just 30 days.

While it is appreciated that the manufacturer of Stemuderm, Solvaderm, offers a money back guarantee on all their products including this one, we doubt that anyone would have a reason to return it. More than just a wrinkle cream, this truly is a multi-action skin treatment that can be used by individuals of all ages, whether they want to reverse existing damage and restore a youthful complexion, or prevent lines, wrinkles, and discoloration from developing in the first place.


Stemuderm customer reviews over the internet

Stemuderm Reviews
4.5/5 (8327 Ratings)
“My Skin Feels Silky Smooth, Young, And Lively, Thanks To Stemuderm!”

Sherri L., Age 47

  • Jo K.

    A Little Goes A Long Way

    Jo K. five-stars

    “In the past anytime I purchased an antiaging facial cream I would slather on thick amounts of it on my face in hopes of getting a superior result, but in reality, it turns out that it doesn’t really make a difference. Since I started using Stemuderm the first appreciate it was the fact that it does not take a large amount to get the job done. In fact, an amount smaller than a quarter is sufficient for application to your entire face. Of course, it also has to be very effective at doing its job or as I wouldn’t even be using it. It is excellent at hydrating my skin, and overall the appearance of fine lines around my eyes and mouth have been minimized. You do need to be consistent in using it, however, I learned this the hard way because I was using it once every couple of days and was not seeing anything, but once I started using it daily the results quickly became noticeable.”


#2.Miami MD

(4.2/5) 4625 Reviews
Diminishes Wrinkles & Fine Lines 89%
Promotes Skin Cell Regeneration 90%
Boosts Hydration 87%
Promotes Good Skin Health 88%
Improves Skin Tone & Texture 87%


  • Has many positive customer reviews
  • It was formulated by doctors


  • It is only available from the official website
  • The customer service department may be hard to contact
  • It may irritate sensitive skin
  • Ingredient amounts aren’t disclosed

The Bottom Line

Overall, the anti-aging treatment Miami MD appears to be a well-made and not overly expensive cream that provides multiple benefits for the skin. However, there are some negative aspects regarding the product too, with reports of it causing irritation for individuals with sensitive skin, and even a few consumers saying it made their complexion dry, which is the opposite of what a cream of this type should do. It would also be helpful if the manufacturer offered free samples of their cream and while there is a refund policy, some individuals have said that contacting the company’s customer service department is difficult.


#3. Drmtlgy

(3.9/5) 4235 Reviews
Diminishes Wrinkles & Fine Lines 88%
Promotes Skin Cell Regeneration 84%
Boosts Hydration 85%
Promotes Good Skin Health 83%
Improves Skin Tone & Texture 82%


  • Products in the range are suitable for all skin types
  • There is a 60-day money back guarantee


  • Drmtlgy products aren’t available in retail stores
  • Clinical study data for product formulas is not available
  • Drmtlgy is more expensive than comparable brands
  • Independent customer reviews are limited

The Bottom Line

The Drmtlgy brand offers several different skincare treatments, including a cleanser, SPF cream, and Needle-less serum, which according to the manufacturer is their best-selling product. The website for the brand is well-produced and reasonably informative and the formulas certainly contain some popular anti-aging key ingredients. However, the products are more expensive than similar brands and there is no solid evidence of successful clinical results provided on the website for prospective customers to review before making a purchase.


- DermaFreeze365 Customer Reviews
  • Stella: Absolutely love this wrinkle cream! Must buy product.
    Star Ratings
  • Willow: I am truly amazed by the effectiveness. Fully Satisfied.
    Star Ratings
  • Lucy: For smooth and wrinkle free skin. Good things comes in small packages.
    Star Ratings
  • Eliana: Light weight formula for the perfect skin. Excellent product.
    Star Ratings
  • Kennedy: Simply luxury to the skin. Very very nice amazing product.
    Star Ratings
  • Quinn: In love with my skin after using this. Reliable and good for skin.
    Star Ratings

Final Words

DermaFreeze365 is a moderately-priced skincare formulation designed to instantly diminish the appearance of common signs of skin aging, including fine lines, wrinkles, sagginess, and hyperpigmentation. It is formulated with several key ingredients, top among them being aminobutyric acid, an amino acid.

DermaFreeze365 Reviews online, while few have contained many negatives. Only try it after considering the cons of the product, such as the use of potentially damaging ingredients, the lack of independent studies and free trials, alongside the skin-enriching results it could offer.

We would recommend consulting your healthcare provider and perhaps looking for similar products in the same category.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Choice’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

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DermaFreeze365 Reviews – Does This Product Really Work?
DermaFreeze365 User Review Rating
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DermaFreeze365 Reviews – Does This Product Really Work?
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