R45 The Reversal Reviews – Does This Product Really Work?

4.3/ 5.0

R45 The Reversal is a 3-phase retinol night lotion that may brighten, smoothen, and tighten your skin for a firm, youthful appearance.


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Overview Of R45 The Reversal

Although there are some steps you might take to avert early skin aging, deep lines, wrinkles, and age spots ultimately happen to everybody at a certain age. Besides natural aging, some external aggressors such as UV rays, pollution, and smoking may speed up wrinkles and fine lines formation.

Although there is no way to stop the aging process, there are products that may slow down the process and help you regain your youthful skin. R45 The Reversal is a 3-phase night cream that might address the symptoms of aging. R45 The Reversal Reviews show that people who used the products noticed a visible skin change and recommend it to a friend.

How Does R45 The Reversal Work?

R45 The Reversal is a three-phase night cream that utilizes a patented booster system that may deliver higher retinol concentrations with each phase, enabling even the most sensitive skin to enjoy maximum outcomes. You should use one phase for about two weeks, allowing your skin to build endurance. The manufacturer indicates that it is a well-functioning retinol-booster you might only need twice a year. Within 45 days of application, this night cream may minimize the appearance of wrinkles and deep lines, leaving you with younger-looking skin.

Additionally, it might fade discolorations, age, and sunspots, resulting in a brighter even tone complexion. R45 The Reversal might tighten and reduce enlarged pores. Over and above that, this anti-aging lotion may mimic the smoothening benefits of retinol without being harsh on the skin. Thus, it might smoothen and firm your face for a fresh, uplifted look.

The manufacturer claims that it is suitable for all skin types. Moreover, each R45 The Reversal phase is stronger than the previous one. Retinol concentrations increase with each phase and may help your skin deal with stubborn aging plateaus. In phase 2, the retinol is 50% stronger, while in phase 3, it is stronger.

Who Is The Manufacturer Of R45 The Reversal?

BeautyBio designs this retinol anti-aging night cream. They claim that they only produce clean products backed by science. BeautyBio boasts of producing prestige formulas for global-renowned brands in their founder’s family-owned cosmetic lab.

Their mission is to make clinically verified formulas using the most potent ingredients.


Reversal Review – Health Web Magazine Images

What Are The Ingredients In R45 The Reversal?

Some of the constituents you might find in this formula include:

TriGLO®  – This is a retinol complex that the manufacturer claims mimics retinol’s brightening and smoothening effects. Therefore, it might fight aging signs and brighten the skin.
Retinol  It might brighten and smoothen your skin. Additionally, research suggests that retinol[1] may improve the appearance of wrinkles.
Growth Factor Stimulant Serum  – This is a peptide complex that may strengthen your skin’s proteins, moisturize the skin, and protect it from free radical damage. A study demonstrated that peptides complex has anti-aging effects.
Safflower Seed Oil  – This oil[2] may aid in balancing sebum levels in your skin, reducing breakouts. Also, it might create a shielding barrier to lock in moisture. A study indicates that safflower seed oil may prevent photo-aging and act as an anti-wrinkle agent.

The Science Behind R45 The Reversal

R45 The Reversal uses a proprietary retinol complex, TriGLO® that may deliver retinol benefits to your skin without harsh effects. It is a friendly retinol molecule that may allow the skin to adjust to different retinol concentrations in each phase. Retinol may target those ugly aging signs like wrinkles, fine lines, hyperpigmentation, and enlarged pores.

Moreover, it might prevent collagen and elastin breakdown, tightening the skin. The manufacturer states that a clinical study shows that retinol may minimize the appearance of wrinkles and fine lines by 45%. Also, in a consumer perception survey, most people reported an improved look, more radiant and youthful skin.

What Are The Benefits Of R45 The Reversal?

  • R45 The Reversal may smoothen stubborn wrinkles and deep lines.
  • It might help reduce enlarged pores size.
  • This retinol booster may fade hyperpigmentation, age, and sun spots for a brighter even tone complexion.
  • It may promote cell turnover for a fresh, youthful look.
  • R45 The Reversal is a working retinol booster you might only need to wear twice a year.

What Are The Drawbacks Of R45 The Reversal?

  • BeautyBio might not offer free trial samples.
  • R45 The Reversal may not be used by pregnant or breastfeeding women.
  • Some consumers may notice a skin reaction to R45 The Reversal.
  • It may not work for all users.

FAQs: Consumer Questions & Answers

In our research for this report, we found that consumers are frequently asking the following questions online in regard to R45 The Reversal.

BeautyBio claims that it does not add harsh chemicals like sulfates, parabens, oxybenzone, formaldehyde, hydroquinone, and triclocarban. The retinol concentrations increase in each phase allowing the skin to experience retinol benefits with no harsh reactions. Nevertheless, the manufacturer advises against applying this retinol booster while pregnant or breastfeeding.

The total reversal bundle is available on the company's official website and other independent retailers at a competitive cost.

Clean your face and dry it. Rub 1-2 pumps of R45 The Reversal Phase one regeneration complex (side A) plus GFS Serum (side B) on your face. After you are done with phase one, advance to phase two and finish with phase three. Apply your moisturizer. The results are gradual, don't skip any phase or start with phase 2 or 3.

BeautyBio offers a money-back guarantee on any skincare products and for GloPRO® products. Besides, the shipping fee is non-refundable.

R45 The Reversal contains a retinol complex, TriGLO®, which offers the skin retinol benefits without causing harsh effects. Also, R45 The Reversal ingredients are not tested on animals.

There are no reported side reactions of this retinol night cream.

The manufacturer states that this 3-phase formula is clinically proven to smoothen wrinkles and fine lines and fade discoloration for a youthful even tone skin.

What Are Consumers Saying About R45 The Reversal?

R45 The Reversal Reviews reported that people who applied the cream noted a positive change even with the 1st phase. It helped fade acne scars and cleared their skin. However, some consumers indicated that the price was outrageous, the containers were barely full, and it didn’t lighten any part of their skin.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Rating Table Rating Table

Our Top Products

Try it now
Stemuderm Rating
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Produces visible results in less than 2 weeks
  • 100% of users experienced a reduction in wrinkle depth
  • Firms skin and restores elasticity
  • Provides long-lasting hydration to eliminate dryness
  • Supports an increase in collagen and elastin production
  • Reduces repetitive muscle movements to stop wrinkle development
  • Strengthens the protective skin barrier
  • Drastically improves long-term skin health
  • Prevents damage from toxins, pollutants, and environmental factors
  • Can be used on all skin types, including sensitive
  • All key ingredients are backed by solid clinical data
  • Manufacturer offers a full money-back guarantee and free shipping
  • Customers can try the product by ordering the Quick Starter Travel Pack
  • Customers do not have to sign up for an auto-shipment or subscription plan


  • Stemuderm cannot be purchased in retail stores
  • High consumer demand results in low stock occasionally

The Bottom Line

We looked at numerous brands of wrinkle creams during our process of compiling a list of the top brands on the market, but one treatment stood out from all the others, and that’s Solvaderm’s Stemuderm.

It’s no surprise that Stemuderm is one of Solvaderm’s best selling products when you consider that it visibly improves the appearance of the skin in less than 2 weeks of use! Rich in clinically proven key active ingredients, this dermatologist developed cream works on multiple signs of aging, including deep-set wrinkles across the forehead and around the mouth, fine lines and crow’s feet around the eyes, and even areas of hyperpigmentation such as age spots. Not only that, but within only a few applications, Stemuderm eliminated dry, flaky patches, locking in moisture, and making the skin smooth, hydrated, and soft to the touch.

Stemuderm Before After

Because Stemuderm produces powerful results in such a short period of time, it’s quickly become a consumer favorite with a satisfaction rating of more than 97%. Almost all Stemuderm users say that it’s an essential part of their morning and evening skincare routine and they would never stop using it. Indeed, the individuals who tested the cream as part of our own extensive review process said that they were particularly impressed at how easily Stemuderm could be incorporated into their current regimen, regardless of their skin type. They also noted that, with regular use, Stemuderm not only maintained the dramatic anti-aging effects they’d already achieved within the first initial few weeks of use but continued to improve the overall health and appearance of their skin, making it look refreshed and rejuvenated. Additionally, their complexion became evenly toned, with a complete absence of redness, and a more uniform texture.

When you look at the incredible results of clinical studies performed on the key active ingredients contained in Stemuderm, it’s easy to see why this treatment works as well as it does, with 100% of users seeing a drastic improvement after only a few weeks of use. For example, in one study looking at the anti-aging benefits of Matrixyl 3000, a substance that supports the production of collagen and elastin, participants experienced a 45% reduction in the area occupied by wrinkles. and in another scientific trial, women using a cream containing the peptide Acetyl Hexapeptide-8, demonstrated a decrease in wrinkle depth by as much as 60% within just 30 days.

While it is appreciated that the manufacturer of Stemuderm, Solvaderm, offers a money back guarantee on all their products including this one, we doubt that anyone would have a reason to return it. More than just a wrinkle cream, this truly is a multi-action skin treatment that can be used by individuals of all ages, whether they want to reverse existing damage and restore a youthful complexion, or prevent lines, wrinkles, and discoloration from developing in the first place.

Miami MD
#2 Miami MD
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Has many positive customer reviews
  • It was formulated by doctors


  • It is only available from the official website
  • The customer service department may be hard to contact
  • It may irritate sensitive skin
  • Ingredient amounts aren’t disclosed

The Bottom Line

Overall, the anti-aging treatment Miami MD appears to be a well-made and not overly expensive cream that provides multiple benefits for the skin. However, there are some negative aspects regarding the product too, with reports of it causing irritation for individuals with sensitive skin, and even a few consumers saying it made their complexion dry, which is the opposite of what a cream of this type should do. It would also be helpful if the manufacturer offered free samples of their cream and while there is a refund policy, some individuals have said that contacting the company’s customer service department is difficult.

#3 Drmtlgy
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture


  • Products in the range are suitable for all skin types
  • There is a 60-day money back guarantee


  • Drmtlgy products aren’t available in retail stores
  • Clinical study data for product formulas is not available
  • Drmtlgy is more expensive than comparable brands
  • Independent customer reviews are limited

The Bottom Line

The Drmtlgy brand offers several different skincare treatments, including a cleanser, SPF cream, and Needle-less serum, which according to the manufacturer is their best-selling product. The website for the brand is well-produced and reasonably informative and the formulas certainly contain some popular anti-aging key ingredients. However, the products are more expensive than similar brands and there is no solid evidence of successful clinical results provided on the website for prospective customers to review before making a purchase.

Your skincare routine is only as good as the products you use. Good, high-quality products are safe and effective and may come in particular formulations for sensitive skin and other issues. They can improve the texture and appearance of your skin while protecting it from the effects of the sun, pollutants, and other problems that can also have a negative impact on your health. Below you will find our subjective assessment of the R45 The Reversal based on the strength of the available information and our estimation of its efficacy for the R45 The Reversal.

R45 The Reversal
R45 The Reversal
  • Diminishes Wrinkles & Fine Lines
  • Promotes Skin Cell Regeneration
  • Boosts Hydration
  • Promotes Good Skin Health
  • Improves Skin Tone & Texture

Overall Rating

Try It

Stemuderm - A Better Alternative?

Diminishes Wrinkles & Fine Lines
Promotes Skin Cell Regeneration
Boosts Hydration
Promotes Good Skin Health
Improves Skin Tone & Texture

In as little as 28 days of regular use, Stemuderm dramatically reduces signs of aging on all areas of the face, including the forehead, cheeks, and around the mouth and eyes.

Stemuderm transforms the skin within weeks, making it visibly firmer, evenly toned, and overall more youthful. Stemuderm also provides long-lasting protection for the skin with its inclusion of innovative plant-based growth enzymes which, as numerous studies have shown, radically slow the aging process and increase skin cell longevity. When used twice a day as recommended by the manufacturer, Stemuderm has been proven to produce significant results, with many users seeing benefits within the first few applications.

You can find out more about Stemuderm now.

Read More About Stemuderm Nowarrow

Final Words

R45 The Reversal is an award-winning retinol night lotion, as stated by the maker. It uses a patented retinol booster that may ensure you enjoy retinol benefits gradually with no harsh effects. BeautyBio claims that it is a functioning anti-aging cream you might only need to wear twice a year.

This retinol booster lotion may smoothen wrinkles, fine lines and firm your skin for a youthful, uplifted look. Furthermore, it might reduce the size of enlarged pores and fade hyperpigmentation for a brighter even tone complexion.

Nevertheless, some R45 The Reversal Reviews reported that it didn't work. Also, they stated that the bottles were barely full and did not last for two weeks as indicated. Besides, BeautyBio might not give a free trial. Also, nursing and pregnant women should not apply this retinol night cream. So, always remember to research more about R45 The Reversal and consult a doctor before use.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Choice’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.


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