Genesphere Review – Does this Product Really Work?

Genisphere is an anti-aging product formulated with a selection of ingredients that may probably help to fight off the appearance of wrinkles, fine lines, age spots, and other aging signs.


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Overview Of Genesphere

According to the brand, Genisphere is formulated with ingredients known to improve aging signs such as wrinkles, fine lines, age spots, and saggy skin. The cream is supposed to be a replacement for invasive and painful procedures such as plastic surgeries, dermal fillers, and botox.

The brand further goes on to claim that when used as directed, massive improvements might be observed on the skin in as little as hours. 

Anti-aging formulations have claimed a whole lot of things in the past but left many users disappointed by their sub-par performance even with the often prohibitive pricing. Therefore, as expected, we want to be careful of products with too-good-to-be-true claims.

In this article, we’ll review Genesphere, the claims, ingredients, possible side effects, pros and cons of usage, and pricing.
Genesphere reviews will also be discussed alongside other details to help us arrive at our conclusion on the product. Had any experience with the Genesphere? Let us know in the comment section below. 

How Does Genesphere Work?

The brand claims that through its unique MicroSome Delivery System, beneficial absorbent spheres are carried into the skin where it goes deep and absorbs the body’s natural moisture to gently lift and erase the wrinkles and other visible facial aging signs.

The product is said to be a safer alternative to invasive and painful dermal fillers, botox, and facelift surgeries. 

Who Is The Manufacturer Of Genesphere?

Genesphere is formulated and manufactured by Biologic Solutions, a skincare and health product company. The brand makes a wide range of products sold online and in physical stores. 


Genesphere Review – Health Web Magazine Images

What Are The Ingredients In Genesphere?

AcquaCell is the main ingredient in the Genesphere. It is a complex consisting of watermelon rind extract, lentil fruit extract, and apple extract. All of these ingredients and their supposed beneficial properties will be discussed here.

Watermelon rind – Watermelon rind is included in skincare and anti-aging formulation for its citrulline content. In studies, citrulline is essential to filaggrin function, hence, a vital part of the skin’s water-based moisturizing complex.

It is not clear if the amount contained in this formulation will help users achieve the same effect on their skin.

Lentil extract – Lentil extract[1] is one of the key ingredients in some anti-aging skin care formulations. It is used for its oligosaccharides content and also contains vitamin B5.

Both are known to improve the skin condition by lessening the appearance of dilated pores, wrinkling for a younger-looking and more refined texture.

Like the watermelon rind, we are not sure how much of the ingredient is contained as quantity often determines many natural ingredients’ effectiveness.

Apple Extract – Apple extract[2] is involved in anti-aging formulations for its high antioxidant content required for protection against free radicals. In studies, free radical damage has been linked to premature aging, and the extract is supposed to help the skin maintain youthful elasticity longer.

The Science Behind Genesphere

According to the brand, the anti-aging formula’s microscopic carrier transports hyaluronic spheres into the epidermis, where they draw in up to 1000 times their weight in natural moisture derived from your body, thereby smoothing wrinkles from within.

This is said to be made possible through AquaCel, the breakthrough ingredient containing moisture-attracting ingredients that help trap and preserve moisture. Hence, the skin stays hydrated, plumped, and free of wrinkles and age lines even while you sleep. 

What Are The Benefits Of Genesphere?

  • It contains ingredients that may help combat wrinkles, fine lines, and other aging signs.
  • The product may improve skin elasticity.
  • It may also improve overall skin condition.
  • Genesphere is manufactured by a known brand.
  • The product is reasonably-priced.

What Are The Drawbacks Of Genesphere?

  • No third-party clinical studies on the product.
  • It may not work as claimed for all users.
  • The exact quantity of key ingredients is not stated.

FAQs: Consumer Questions & Answers

Answered here are some of the common questions about Genesphere we found online during our research.

The cream is formulated with known natural ingredients, and so far, there have been no complaints of severe adverse effects from use. However, as with all topical skincare formulations, we advise users to avoid using Genesphere on broken or skin with unhealed conditions.

It is also not suitable for use by people under 18. Before use, confirm that you are not allergic to any of the ingredients in the formulation and if you are, avoid using the product. Also, discontinue use immediately if you notice any severe side effects from use.

Genesphere is within the price range of many anti-aging facial formulations. It may be purchased on the brand's official store and third-party retail sites.

The brand's recommended direction for application is each morning, apply the cream evenly on the entire face after washing and drying. The brand encourages users good improvement within weeks with regular use.

The brand offers buyers exchange or refunds if returned within a month of purchase. There is also no mention of a free trial.

Genesphere isn't different from many facial anti-aging formulations out there. The main ingredients and complex are quite basic and might be found in many other formulations. On pricing, it is also within the price range of many similar products.

While no side effects have been reported from product use, buyers are to keep in mind people react differently to products. Some will be sensitive to specific ingredients, and some will not.

Generally, though, none of the key ingredients have been reported to cause severe side effects from use. But you still should confirm that all of the ingredients are suitable for you. 

We think Genesphere might be good if you do not mind that it does not contain any exceptional ingredients and are not looking to spend too much on an anti-aging formula. We like that the product is almost reasonably-priced for a product in its quality range even though we think it may be more effective with known and common anti-aging ingredients.

What Are Consumers Saying About Genesphere?

Genesphere reviews are mixed and similar to the ones on products in its quality range. While several reviewers claimed to have noted improvements in their skin’s color and appearance of wrinkles, a few on the other complained that it did nothing to improve their aging signs.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Choices of 2022


StemudermBest-Selling Anti-Wrinkle Dermatological Formula!

Stemuderm Reviews
4.5/5 (8327 Ratings)
Diminishes Wrinkles & Fine Lines 98%
Promotes Skin Cell Regeneration 99%
Boosts Hydration 98%
Promotes Good Skin Health 98%
Improves Skin Tone & Texture 97%


  • Produces visible results in less than 2 weeks
  • 100% of users experienced a reduction in wrinkle depth
  • Firms skin and restores elasticity
  • Provides long-lasting hydration to eliminate dryness
  • Supports an increase in collagen and elastin production
  • Reduces repetitive muscle movements to stop wrinkle development
  • Strengthens the protective skin barrier
  • Drastically improves long-term skin health
  • Prevents damage from toxins, pollutants, and environmental factors
  • Can be used on all skin types, including sensitive
  • All key ingredients are backed by solid clinical data
  • Manufacturer offers a full money-back guarantee and free shipping
  • Customers can try the product by ordering the Quick Starter Travel Pack
  • Customers do not have to sign up for an auto-shipment or subscription plan


  • Stemuderm cannot be purchased in retail stores
  • High consumer demand results in low stock occasionally

The Bottom Line

We looked at numerous brands of wrinkle creams during our process of compiling a list of the top brands on the market, but one treatment stood out from all the others, and that’s Solvaderm’s Stemuderm.

It’s no surprise that Stemuderm is one of Solvaderm’s best selling products when you consider that it visibly improves the appearance of the skin in less than 2 weeks of use! Rich in clinically proven key active ingredients, this dermatologist developed cream works on multiple signs of aging, including deep-set wrinkles across the forehead and around the mouth, fine lines and crow’s feet around the eyes, and even areas of hyperpigmentation such as age spots. Not only that, but within only a few applications, Stemuderm eliminated dry, flaky patches, locking in moisture, and making the skin smooth, hydrated, and soft to the touch.

Because Stemuderm produces powerful results in such a short period of time, it’s quickly become a consumer favorite with a satisfaction rating of more than 97%. Almost all Stemuderm users say that it’s an essential part of their morning and evening skincare routine and they would never stop using it. Indeed, the individuals who tested the cream as part of our own extensive review process said that they were particularly impressed at how easily Stemuderm could be incorporated into their current regimen, regardless of their skin type. They also noted that, with regular use, Stemuderm not only maintained the dramatic anti-aging effects they’d already achieved within the first initial few weeks of use but continued to improve the overall health and appearance of their skin, making it look refreshed and rejuvenated. Additionally, their complexion became evenly toned, with a complete absence of redness, and a more uniform texture.

Stemuderm Before After

When you look at the incredible results of clinical studies performed on the key active ingredients contained in Stemuderm, it’s easy to see why this treatment works as well as it does, with 100% of users seeing a drastic improvement after only a few weeks of use. For example, in one study looking at the anti-aging benefits of Matrixyl 3000, a substance that supports the production of collagen and elastin, participants experienced a 45% reduction in the area occupied by wrinkles. and in another scientific trial, women using a cream containing the peptide Acetyl Hexapeptide-8, demonstrated a decrease in wrinkle depth by as much as 60% within just 30 days.

While it is appreciated that the manufacturer of Stemuderm, Solvaderm, offers a money back guarantee on all their products including this one, we doubt that anyone would have a reason to return it. More than just a wrinkle cream, this truly is a multi-action skin treatment that can be used by individuals of all ages, whether they want to reverse existing damage and restore a youthful complexion, or prevent lines, wrinkles, and discoloration from developing in the first place.


Stemuderm customer reviews over the internet

Stemuderm Reviews
4.5/5 (8327 Ratings)
“My Skin Feels Silky Smooth, Young, And Lively, Thanks To Stemuderm!”

Sherri L., Age 47

  • Jo K.

    A Little Goes A Long Way

    Jo K. five-stars

    “In the past anytime I purchased an antiaging facial cream I would slather on thick amounts of it on my face in hopes of getting a superior result, but in reality, it turns out that it doesn’t really make a difference. Since I started using Stemuderm the first appreciate it was the fact that it does not take a large amount to get the job done. In fact, an amount smaller than a quarter is sufficient for application to your entire face. Of course, it also has to be very effective at doing its job or as I wouldn’t even be using it. It is excellent at hydrating my skin, and overall the appearance of fine lines around my eyes and mouth have been minimized. You do need to be consistent in using it, however, I learned this the hard way because I was using it once every couple of days and was not seeing anything, but once I started using it daily the results quickly became noticeable.” **


#2.Miami MD

(4.2/5) 4625 Reviews
Diminishes Wrinkles & Fine Lines 89%
Promotes Skin Cell Regeneration 90%
Boosts Hydration 87%
Promotes Good Skin Health 88%
Improves Skin Tone & Texture 87%


  • Has many positive customer reviews
  • It was formulated by doctors


  • It is only available from the official website
  • The customer service department may be hard to contact
  • It may irritate sensitive skin
  • Ingredient amounts aren’t disclosed

The Bottom Line

Overall, the anti-aging treatment Miami MD appears to be a well-made and not overly expensive cream that provides multiple benefits for the skin. However, there are some negative aspects regarding the product too, with reports of it causing irritation for individuals with sensitive skin, and even a few consumers saying it made their complexion dry, which is the opposite of what a cream of this type should do. It would also be helpful if the manufacturer offered free samples of their cream and while there is a refund policy, some individuals have said that contacting the company’s customer service department is difficult.


#3. Drmtlgy

(3.9/5) 4235 Reviews
Diminishes Wrinkles & Fine Lines 88%
Promotes Skin Cell Regeneration 84%
Boosts Hydration 85%
Promotes Good Skin Health 83%
Improves Skin Tone & Texture 82%


  • Products in the range are suitable for all skin types
  • There is a 60-day money back guarantee


  • Drmtlgy products aren’t available in retail stores
  • Clinical study data for product formulas is not available
  • Drmtlgy is more expensive than comparable brands
  • Independent customer reviews are limited

The Bottom Line

The Drmtlgy brand offers several different skincare treatments, including a cleanser, SPF cream, and Needle-less serum, which according to the manufacturer is their best-selling product. The website for the brand is well-produced and reasonably informative and the formulas certainly contain some popular anti-aging key ingredients. However, the products are more expensive than similar brands and there is no solid evidence of successful clinical results provided on the website for prospective customers to review before making a purchase.


- Genesphere Customer Reviews
  • Layne: Great anti ageing cream. It helps to reduce skin damage.
    Star Ratings
  • Leanna: Happy for reducing my wrinkles and fine line. Try it once and believe if it actually works.
    Star Ratings
  • Kimber: It is very smooth and moisturizing! Works as a good moisturizer.
    Star Ratings
  • Clare: Amazing Results in one Week-Wow. Loved the product performance.
    Star Ratings
  • Rivka: Cream goes on well and feels great. Good cream for matured skin.
    Star Ratings
  • Lillie: I really like how easy it gets absorbed. Impressive product.
    Star Ratings

Final Words

Genesphere contains ingredients backed by clinical studies. However, these ingredients aren't exactly exceptional. While they hold anti-aging qualities when included in the right amounts, we think they may be more effective with more known anti-aging ingredients.

Genesphere reviews on its part have been mixed. Many users liked that it is moderately-priced. Also, various reviewers claimed to have seen changes in their skin color and appearance of wrinkles.

However, there are also testimonials claiming that the product did nothing to promote their aging signs. We would recommend consulting your doctor about genesphere and perhaps look for some similar products of the same kind.

**The above is a subjective review. Our opinion of the product’s efficacy was based on independent research and information.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

Disclosure of Material Connection : Products shown in the section titled ‘Our Top Choice’ are those that we promote as the owner and/ or reseller and does not represent all products currently on the market or companies manufacturing such products. This information is disclosed in accordance with the Federal Trade Commission’s 16 CFR, Part 255 “Guides Concerning the Use of Endorsements and Testimonials”. We would like to make it clear that any and all links featured in this section are sales links; whenever a purchase is made via one of these links, we will receive compensation.

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Genesphere Review – Does this Product Really Work?
Genesphere User Review Rating
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Genesphere Review – Does this Product Really Work?
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