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Best Glutathione Supplements to Tackle Skin Aging & Pigmentation

Glutathione Supplements

Glutathione for the skin - (Image Credit: Shutterstock)

Story At-A-Glance
  • Glutathione is an antioxidant naturally present in the body that fights against free radical damage. It protects the body from toxins and pollutants.
  • Glutathione is produced by the liver and requires different enzymes and nutrients for optimal synthesis.
  • Low glutathione levels in the body due to nutritional deficiencies or aging can cause skin issues and organ dysfunction.
  • To combat lowered glutathione production in the body, you can consume oral glutathione supplements.
  • Serums and creams with antioxidants like vitamin C can also fight skin aging and can boost glutathione levels.
  • These glutathione supplements can reduce wrinkles, pigmentation, fine lines, and other signs of aging.

What Is Glutathione?

Glutathione is a potent antioxidant naturally present in the human body. It is processed by the liver and is made up of 3 amino acids – glycine, cysteine, and glutamic acid.

Glutathione is found abundantly in different parts of the body. It plays a role in tissue generation and repair, immune response, and protein synthesis, ensuring the optimal physical health of various organs.

Moreover, it also protects the body against free radical damage. Our body encounters different free radicals in the form of pollutants, toxic impurities in food, and other environmental stressors.

Glutathione guards the body against the toxic effects of these pollutants. It can also protect the skin from aging due to free radical damage. Consuming glutathione for skin is a common practice.

How Is Glutathione Made by the Body?

Glutathione is synthesized in the human body from a compound called homocysteine. The liver converts this substance into glutathione with the help of multiple enzymatic reactions.

Each reaction needs the help of cofactor nutrients like magnesium and vitamin B6. To maintain optimal levels in the body, you need to have the appropriate balance of various enzymes and cofactors along with homocysteine. 

According to studies, glutathione is found abundantly in the body. Present in almost as much concentration as glucose in human cells, glutathione is one of the essential components that protect the body from toxins, inflammatory damage, and aging.

As we grow older, its production in our body may slow down, which can lead to skin aging and poor organ function.

Low glutathione levels may cause dullness and hyperpigmentation on the skin and inflammatory disorders in the body. You can use the best glutathione supplement to protect your health.

Glutathione for Skin

What Are the Best Glutathione Supplements?

The best glutathione supplements for the skin are ones with a stable formula that prevents oxidation of the substance.

Glutathione is a substance that gets oxidized quickly when exposed to the environment. It needs to be formulated in such a manner that prevents its oxidation.

One example is oral supplements that contain liposomal glutathione. In these supplements, lipid spheres enclose glutathione to protect it from oxidative damage.

Alternatively, you can also consider oral supplements or topical creams with antioxidants that encourage glutathione production in the body.
For example, vitamin C can convert oxidized glutathione back to its active state. Vitamin C serums and supplements can also boost glutathione levels in the body.

Our Picks for the Top 6 Glutathione Supplements

1. Juvabrite

Juvabrite Reviews

To compensate for glutathione deficiency in the body, you need supplements high in antioxidants.

Juvabrite is a top-rated skincare product, containing plant-based ingredients that fight against oxidative stress. It includes seaweed extracts with anti-inflammatory properties along with herbs and hyaluronic acid.

This cream brightens the skin and reduces wrinkles, pigmentation, and other signs of aging. The customer reviews are very favorable, which is why Juvabrite tops our list of glutathione supplements for the skin.

2. Natures Craft’s Best Glutathione Supplement

Natures Craft’s Best Glutathione Supplement

Natures Craft’s Best Glutathione Supplement is a dietary supplement with L-glutathione and milk thistle.

While glutathione fights oxidative stress, the herbal extracts of milk thistle may improve liver health.

Furthermore, this supplement claims to fight aging and lighten the skin. It also claims to improve energy and focus.

3. Skin Daily Niacinamide Serum for Face

Skin Daily Niacinamide Serum for Face

Niacinamide or vitamin B3 is a nutrient that can boost glutathione levels in the body.

Furthermore, it can also tackle skin aging and brighten the skin. The Skin Daily Niacinamide Serum with 5% niacinamide also contains hyaluronic acid that plumps up the skin and reduces wrinkles.

This serum could be one of the best glutathione supplements for the skin.

4. Seoul Ceuticals Day Glow Serum

Seoul Ceuticals Day Glow Serum

20% Vitamin C + Hyaluronic Acid Serum – Vitamin C is antioxidant that could reverse pigmentation and skin aging. It may also reactivate oxidized glutathione in the body, thereby boosting its levels.

The Seoul Ceuticals Day Glow Serum is a Korean skincare product with 20% vitamin C and HA. This K Beauty serum claims to reduce fine lines, wrinkles, sun spots, and pigmentation. It might be the best glutathione supplement to fight against skin aging.

5. Sanar Premium Collagen Peptides with Vitamin C & E

Sanar Premium Collagen Peptides with Vitamin C & E

Another option for top glutathione supplements for the skin in oral form is the Sanar Premium Collagen Peptides.

This anti-aging skin supplement contains collagen peptides, vitamin C, vitamin E, and Rosehip extracts. It claims to improve skin elasticity and offer smooth, youthful skin.

It also claims to improve nail and bone health. This supplement may be able to help you if you are facing skin aging due to glutathione deficiency.

6. Emily Bright Glutathione Whitening Pills

Emily Bright Glutathione Whitening Pills

Emily Bright Glutathione Whitening Pills contain 2000 mcg glutathione along with licorice, cinnamon, and papaya extracts.

These pills claim to perform better than skin lightening creams because they tackle pigmentation from within the body.

Moreover, they fight against free radical damage, prevent aging, and brighten the skin. The reviews of this product by consumers are quite positive too. These pills have made it to our list of best glutathione supplements for the skin.

FAQs About Glutathione Supplements

Glutathione is a naturally occurring substance in the human body that is essential for optimal health. It is considered safe when consumed as per the recommended dosage. But, long-term consumption can sometimes cause zinc deficiency in the body.

It may also trigger asthma attacks or allergic reactions in some rare cases. If you are on any other medications or supplements, consult a doctor before trying glutathione supplements.

According to studies[1], glutathione can reduce pigmentation as well as wrinkles. You may consider glutathione supplements if you are struggling with uneven pigmentation or fine lines on the skin. Antioxidant serums with vitamin C or niacinamide may also help.

Glutathione supplements may lighten the skin by inhibiting tyrosinase, the enzyme responsible for melanin production. But, the results may vary across individuals and may take months to be visible in some cases. You should use glutathione as a skin-lightening treatment only after consulting a doctor.

Experts advise against consuming glutathione if you are pregnant or breastfeeding. Consult your doctor before consuming any supplements during this phase.

Oral pills with stable forms of glutathione are the best way to supply it to your body. However, consuming antioxidant-rich foods and multivitamin supplements can also boost your glutathione levels naturally.

The Bottom Line – You Can Beat Aging with the Best Glutathione Supplements!

Glutathione is an essential substance for our overall physical health. But the first signs of glutathione deficiency could show up on our skin.

These include hyperpigmentation, dullness, and wrinkles. However, you do not have to succumb to aging. Fight it with glutathione supplements!

The best type of glutathione for the skin is in the form of oral pills. However, serums and creams that are rich in antioxidants are effective anti-aging treatments too.

By boosting your antioxidant and glutathione intake, you can combat aging and maintain good physical health. So, don’t consider aging to be a losing battle. With balanced nutrients and supplements, you can preserve your overall health and skin!

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In keeping with our strict quality guidelines, we only cite academic research institutions, established health journals, or peer-reviewed studies in our content. You will be able to find links to these sources by clicking the numbers in parentheses (1, 2, etc.) that appear throughout our content.

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All Health Web Magazine content is thoroughly reviewed and/or fact-checked by a team of health industry experts to ensure accuracy.

In keeping with our strict quality guidelines, we only cite academic research institutions, established health journals, or peer-reviewed studies in our content. You will be able to find links to these sources by clicking the numbers in parentheses (1, 2, etc.) that appear throughout our content.

At no time do we advise any of our readers to use any of our content as a substitute for a one-on-one consultation with a doctor or healthcare professional.

We invite you to contact us regarding any inaccuracies, information that is out of date or any otherwise questionable content that you find on our sites via our feedback form.